Whole-biomass biotechnology · South Africa

Watermelon-derived ingredients. Four fields of opportunity.

We develop liquid extract and fibre from whole watermelon for cosmetic ingredient evaluation and potential nutraceutical, food and medical research applications.

Watermelon biotechnology visual with fresh watermelon, green leaves and molecular-inspired design
What we produce

Liquid extract. Plant fibre. Ingredients with purpose.

Whole-watermelon bioconversion produces a liquid extract and a fibre-rich solid fraction. We develop these materials as starting points for partner-led ingredient and product development.

Liquid extract

A liquid material derived from cultivated watermelon through our bioconversion process. Its composition and analytical profile guide ingredient evaluation, formulation work and biological research.

Fibre fraction

The recovered fibre-rich solid material provides a second development stream. Potential uses include food ingredient and biomaterial research, with composition and functional properties to be assessed for each use.

Where the outputs could be used

Four application areas.

Cosmetics are a current evaluation focus. Nutraceutical, food and medical research applications form the wider development opportunity.

Cosmetics

Skincare and topical formulations

Evaluate the liquid extract as an ingredient for creams, serums and other topical formulations. Development work can examine formulation compatibility, stability, skin tolerance and performance.

For: Cosmetic formulators, skincare brands and ingredient developers.

Nutraceuticals

Nutritional ingredient development

Explore whether the extract or further-developed fractions could support supplement and nutritional formulations. Priorities include composition, suitable delivery format, oral safety, stability and evidence for any proposed benefit.

For: Supplement developers and nutrition research teams.

Food

Food ingredients and fibre applications

Investigate the extract and fibre fraction as candidate ingredients for food and beverage development. The next questions include taste, texture, microbiological quality, processing compatibility and shelf life.

For: Food manufacturers, beverage developers and food scientists.

Medical research

Hydrogels, topical delivery and skin-repair research

Investigate the materials in hydrogel, topical-delivery and skin-repair research programmes. These are research directions requiring biological testing and application-specific development.

For: Biomaterials researchers, university laboratories and medical development partners.

These are ingredient development and research pathways. Suitability, safety and performance must be established for each intended use; food, supplement and medical applications are not presented as approved finished products.

One whole fruit. A wider field of possibility.

Whole biomass

A development approach focused on using more of the cultivated watermelon fruit.

No added process water

Designed around the fruit's native moisture during the conversion process.

Evidence-led development

Measure, compare and improve through analytical characterisation.

What is La Grace Bio?

A Cape Town biotechnology company.

La Grace Bio (Pty) Ltd develops a whole-biomass bioconversion platform for cultivated watermelon (Citrullus lanatus). Founded by Pierre van der Merwe, the company brings together native-moisture processing and analytical characterisation to explore bio-based ingredient development.

Our focus connects physical outputs to ingredient development, research and licensing across cosmetics, nutraceuticals, food and medical research. The platform is associated with international patent application PCT/IB2025/061059.

From biomass to value

Whole-biomass bioconversion. From input to ingredient.

Plant materials vary with growing conditions and handling. Our development approach is process-defined so outputs can be characterised, compared and improved.

01 / Source

Start with traceable biomass.

Cultivated Citrullus lanatus is the starting material. Knowing the input is the first step toward understanding the output.

02 / Transform

Let the process create value.

Whole-biomass bioconversion uses the fruit's native moisture. The development process avoids adding water during the core conversion stage.

03 / Characterise

Build a measurable profile.

Analytical testing is used to understand composition and compare samples. That evidence guides development decisions.

Evidence, with context

Progress you can examine.

Composition testing

CPUT analytical work provides a foundation for understanding tested material.

Analytical fingerprinting

Stellenbosch analytical work adds a detailed view of submitted samples' biochemical profiles.

International IP pathway

PCT/IB2025/061059 was filed in October 2025 and remains pending.

September 2026: La Grace Bio advanced to the Top 3 of the Eastern Cape NCIC Waste-to-Value Challenge.

Built for collaboration

A platform for your next development question.

We welcome focused conversations with ingredient developers, formulators, research teams and potential licensees.

  • Ingredient and formulation development
  • Research collaboration
  • Licensing and scale-up
Progress and recognition

Milestones behind the platform.

Article 34 filed

Our PCT Chapter II filing, including Article 34 amendments, was submitted on 4 September 2026 for PCT/IB2025/061059.

GCIP-SA semifinalist

La Grace Bio's development journey includes semifinalist recognition in the Global Cleantech Innovation Programme South Africa.

Eastern Cape NCIC Top 3

Top 3 in the Eastern Cape NCIC Waste-to-Value Challenge, 2026.